Proper storage methods ensure the stability and efficacy of the medication.
I. Storage requirements for oral solution
1. Storage before preparation
(1) Unprepared risdiplam powder should be kept in its original container to avoid moisture.
(2) Store at room temperature; no refrigeration required.
(3) Do not transfer the powder to another container, as this may affect drug stability.
2. Storage after preparation
(1) The oral solution should be protected from light after preparation.
(2) Can be stored at room temperature; no need to refrigerate.
(3) Keep the bottle tightly closed after each use to prevent evaporation or contamination.
3. Precautions during use
(1) The oral solution should be withdrawn using the supplied oral dispenser. Clean and dry the dispenser after each use.
(2) Do not pour the drug directly into another container or mix it with beverages for long-term storage.
(3) The prepared solution should be used within the specified period; discard if expired.
II. Storage requirements for tablets
1. Tablet storage environment
(1) Risdiplam tablets should be stored in the original container, away from direct sunlight and high temperatures.
(2) Keep in a cool, dry place, away from humid areas such as bathrooms and kitchens.
(3) Tablets should be taken promptly after removal and not left exposed to air for long periods.
2. Avoid moisture and contamination
(1) Keep hands dry when removing tablets; do not pour out tablets and return them to the package.
(2) The aluminum blister packaging protects the tablets from moisture; keep the packaging intact until use.
(3) Do not use tablets if they are discolored, chipped, or have an unusual odor.
3. Special instructions for tablets
(1) Tablets can be swallowed whole or dispersed in a small amount of room-temperature water and taken immediately.
(2) Use room-temperature drinking water for dispersion; do not use hot water or acidic beverages.
(3) The dispersed solution should be taken immediately and not stored for later use.
III. General storage precautions
1. Safe storage location
(1) Keep the medication out of reach of children and pets to prevent accidental ingestion.
(2) Store the medication in its original container for easy identification of drug name, strength, and expiration date.
(3) Avoid storing medications in places with significant temperature fluctuations, such as nightstands or cars.
2. Expiration date management
(1) Regularly check the expiration date of medications; discard expired ones promptly.
(2) It is not recommended to transfer more than a few days' supply of medication into a pillbox, as this may affect stability.
(3) Storage conditions for different batches of medication are the same, but they should not be mixed together.
3. Travel carrying advice
(1) When traveling, carry the required dose of medication in its original container, avoiding direct sunlight.
(2) Tablets are suitable for carrying at room temperature; oral solution should not be left in a hot car for extended periods.
(3) When flying, carry the medication in your hand luggage to avoid temperature changes that may occur in checked baggage.
4. Disposal of expired or unused medication
(1) Do not discard expired or unused medication in the trash or flush it down the toilet.
(2) Dispose of it according to local medication take-back regulations; consult a pharmacist or healthcare facility for disposal advice.
(3) Packaging materials (bottles, dispensers, blister packs) should also be sorted and discarded appropriately.
