Canagliflozin Hydrochloride Tablets (Canaglu) is a type of SGLT2 inhibitor, mainly used for the treatment of type 2 diabetes mellitus and its related complications.
Indications for Canagliflozin Hydrochloride Tablets (Canaglu)
Main Indications
Type 2 Diabetes Mellitus: Suitable for patients with type 2 diabetes mellitus who have not achieved adequate results after treatment with dietary therapy and exercise therapy. It should be noted that this medication is only applicable to patients diagnosed with type 2 diabetes mellitus and is not suitable for patients with type 1 diabetes mellitus.
Type 2 Diabetes Mellitus Complicated with Chronic Kidney Disease: Suitable for patients with type 2 diabetes mellitus complicated with chronic kidney disease, excluding those with end-stage renal failure or undergoing dialysis treatment.
Precautions for Use
This medication should be considered for use only when the effects of basic diabetes treatment (dietary therapy and exercise therapy) are still unsatisfactory after full implementation.
For patients with complicated chronic kidney disease, initiation of new treatment should not be started when the estimated glomerular filtration rate (eGFR) is below 30 mL/min/1.73m².
Blood glucose and renal function should be monitored regularly during the treatment process.
Specifications and Properties of Canagliflozin Hydrochloride Tablets (Canaglu)
Preparation Specifications
Canaglu Tablets 100mg: Each tablet contains 102mg of canagliflozin hydrate (equivalent to 100mg of canagliflozin).
Canaglu OD Tablets 100mg: Orally disintegrating tablets, each containing 102mg of canagliflozin hydrate (equivalent to 100mg of canagliflozin). (Note: "OD" stands for "Orally Disintegrating," referring to orally disintegrating tablets.)
Canaglu Tablets 100mg
Appearance: Light yellow film-coated tablets.
Diameter: 7.6mm.
Thickness: 3.4mm.
Weight: 144.3mg.
Canaglu OD Tablets 100mg
Appearance: Light yellow-brown uncoated tablets (orally disintegrating tablets).
Diameter: 9.5mm.
Thickness: 4.4mm.
Weight: 303mg.
Excipient Ingredients
Both dosage forms contain different excipient ingredients, including D-mannitol, hydroxypropyl cellulose, croscarmellose sodium, etc. The specific formula varies depending on the dosage form.
The OD tablets also contain special disintegrants and fragrances to achieve the characteristic of rapid disintegration in the oral cavity.
Storage Method for Canagliflozin Hydrochloride Tablets (Canaglu)
Routine Storage Conditions
Storage Temperature: Store at room temperature.
Light Protection Requirement: No special light protection requirement.
Special Precautions
Medications in PTP (Press-Through Package) should be taken out of the PTP blister before administration to avoid accidental swallowing of the entire package.
The medication should be placed out of the reach of children.
When administering OD tablets, avoid giving them to patients in a recumbent position without water.
The medication should not be used continuously if there is a change in its physical properties.
